Research Interests
LATEST NEWS
Congrats to Laure Guitton-Sert !
August 2025
Laure Guitton-Sert (former post-doc in our team) has been recruited as a lecturer ("maîtresse de conférence") at the University of Toulouse. She will join to Didier Trouche's team at the CBI.
Congrats to Ikrame!
July 2025
Ikrame Lazar has been recruited as a lecturer ("maîtresse de conférence") at the University of Toulouse. She will remain in our team.
"Face Cam"
August 2025
Our local CNRS branch, made a short video in which Gaëlle explains our recent findings and the impact it could generate for medical research.
Congrats to Florian and Emma !
May 2025
Two former PhDs of the team share a co-first authorship on the story where we show that RNA:DNA hybrids at DSBs orginiated from pre-existing RNA and transcriptional repression
When RNA gets involved in DSB repair
July 2025
CNRS biologie highlighted our recenlty published article with content tailored for the general public.
Anne-Laure Fioux is recruited as an engineer
December 2024
Anne-Laure Finoux has been recruited at the CNRS as a research engineer ("ingénieure d'étude"). She works on the genSCAN platform and also in our team. We are glad to have her back!
Time to celebrate
July 2025
It has been a while since we had gathered all together! We had many things to celebrate! So it was a good excuse to organize a BBQ party.
RECENT ARTICLES
May 2025
This article in Nature Cell Biology shows that RNA:DNA hybrids, rather than R-loops, are stabilized at DSBs. Moreover, their formation results from the asymmetric hybridization of pre-existing RNA to the non-resected DNA strand as a consequence of transcriptional repression.
October 2023
This article Nature shows that a novel chromatin compartment forms in response to DSB induction.
April 2022
This article in Nat Comm shows that upon excessive RNA:DNA hybrid accumulation, DNA synthesis is enhanced at DSBs, in a manner that depends on BLM and POLD3