Research Interests
LATEST NEWS
Time to celebrate
July 2025
It has been a while since we had gathered all together! We had many things to celebrate! So it was a good excuse to organize a BBQ party.
Congrats to Ikrame!
July 2025
Ikrame Lazar has been recruited as a lecturer ("maîtresse de conférence") at the University of Toulouse. She will remain in our team.
Congrats to Florian and Emma
May 2025
Two former PhDs of the team share a co-first authorship on the story where we show that RNA:DNA hybrids at DSBs orginiated from pre-existing RNA and transcriptional repression
Anne-Laure Fioux is recruited as an engineer
December 2024
Anne-Laure Finoux has been recruited at the CNRS as a research engineer ("ingénieure d'étude"). She works on the genSCAN platform and also in our team. We are glad to have her back!
RECENT ARTICLES
May 2025
This article in Nature Cell Biology shows that RNA:DNA hybrids, rather than R-loops, are stabilized at DSBs. Moreover, their formation results from the asymmetric hybridization of pre-existing RNA to the non-resected DNA strand as a consequence of transcriptional repression.
October 2023
This article Nature shows that a novel chromatin compartment forms in response to DSB induction.
April 2022
This article in Nat Comm shows that upon excessive RNA:DNA hybrid accumulation, DNA synthesis is enhanced at DSBs, in a manner that depends on BLM and POLD3