Research Interests

Our research aim is to understand the molecular mechanisms responsible for the maintenance of genome integrity. Our lab particularly focuses on DNA double strand break repair in the context of chromatin.


Coline is now a PhD!

Congrats to Coline who defended her PhD viva on December 17th!!

for more pics, click here!

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December 2020

BLM and BIR on bioRxiv

Here you'll find our new story on the Bloom helicase (BLM) and Break-induced replication (BIR) on bioRxiv


May 2020

We are moving lab!

That's it, after more than 2 years of construction, our new building is ready to welcome us!

for more pics, click here!


October 2020

Loop extrusion in the formation of repair foci on bioRxiv

Here you'll find our new story about loop extrusion as a mechanism of DSB foci formation on  bioRxiv

loop extrusion DSB.JPG

May 2020



August 2020

This chapter is part of the Methods in Molecular Biology book and highlights how to analyze HR at the genome-wide level.


February 2020

Studying DNA Double-Strand Break Repair: An Ever-Growing Toolbox 

This review in Frontiers in Molecular Biosciences discusses of the exisiting tools to study DNA double strand break repair

m6A modififed R-loops.JPG

December, 2019

m6A RNA involvment in R-loop regulation  by Aline Marnef

This News and views  in Nature Genetics discusses the recent discovery that R-loops can be m6A modified and the impact on genome stability.