Research Interests
Our research aim is to understand the molecular mechanisms responsible for the maintenance of genome integrity. Our lab particularly focuses on DNA double strand break repair in the context of chromatin.
LATEST NEWS
Summer Night out
Night out with the whole team!
July 2022
Unit retreat
We had a nice time at our unit (MCD) retreat!
March 2022
Sarah, Aude and Ikrame's paper is out!
A POLD3/BLM dependent repair pathway handles DSBs upon the presence of excessive R-loops
April 2022
Emma Lesage PhD Defense
Congrats to Emma Lesage who succesfully obtained her PhD this 13th December!
December 2021
RECENT ARTICLES
April 2022
This article in Nat Comm shows that upon excessive RNA:DNA hybrid accumulation, DNA synthesis is enhanced at DSBs, in a manner that depends on BLM and POLD3
June 2021
This review article in DNA repair discusses about the way DSBs occurring in actively transcribed loci are handled
April 2021
This review article in Nature Cell Biology discusses about the formation and function of R-loops that accumulate in cis to DSBs, especially those induced in transcriptionally active loci.