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chromatin landscape at DSB

Research Interests

Our research aim is to understand the molecular mechanisms responsible for the maintenance of genome integrity. Our lab particularly focuses on DNA double strand break repair in the context of chromatin.

LATEST NEWS

Christmas dinner

We finally had our Christmas dinner in late January!

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January 2023

Halloween cake

As usual Nathalie made us a wonderful Halloween cake!

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October 2022

Congrats Ikrame !

Congrats to Ikrame for the second young researcher prize from the Fonroga foundation

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Novembre 2022

Congrats Nathalie!

Congratulation to Nathalie for her obtention of the grade of "technicienne supérieure"! We celebrated around marvelous food and cakes that she made herself!

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October 2022

RECENT ARTICLES

BLM POLD3 SETX and R-loops DSB.JPG

April 2022

This article in Nat Comm shows that upon excessive RNA:DNA hybrid accumulation, DNA synthesis is enhanced at DSBs, in a manner that depends on BLM and POLD3

DSB in active loci.JPG

June 2021

This review article in DNA repair discusses about the way DSBs occurring in actively transcribed loci are handled

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April 2021

This review article in Nature Cell Biology  discusses about the formation and function of  R-loops  that accumulate in cis to DSBs, especially those induced in transcriptionally active loci.

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