chromatin landscape at DSB Gaelle legube

Research Interests

Our research aim is to understand the molecular mechanisms responsible for the maintenance of genome integrity. Our lab particularly focuses on DNA double strand break repair in the context of chromatin. Oour research is performed at the MCD unit within the CBI in Toulouse, France.

LATEST NEWS

Congrats to Gaëlle for the "prix Allianz" from the french accademy

November 2024

This prize was awarded for her major research achievments, which has led or may lead to clinical applications likely to increase life expectancy through preventive or curative action.

Congrats to Emile

November 2024

Congrats to Emile for his Medal that rewarded the "major French advances in biology" from the Mergier Bourdeix Fondation .

Congrats to Emile

June 2024

Congrats to Emile for his Medal that rewarded the "major French advances in biology"

Welcome to Emile

January 2024

We wish to welcome Emile Al Ghoul who just joined our team as a post-doc!

RECENT ARTICLES

October 2023

Chromatin compartmentalization regulates
the response to DNA damage

This article Nature shows that a novel chromatin compartment forms in response to DSB induction.

April 2022

POLD3/BLM dependent pathway for DSB accumulating excessive R-loops

This article in Nat Comm shows that upon excessive RNA:DNA hybrid accumulation, DNA synthesis is enhanced at DSBs, in a manner that depends on BLM and POLD3