Our research aim is to understand the molecular mechanisms responsible for the maintenance of genome integrity. Our lab particularly focuses on DNA double strand break repair in the context of chromatin.
"Femmes Inspirantes, Femmes remarquables"
On the occasion of the International Day for Women's Rights on March 8 and the establishment of a Month dedicated to gender equality, the City of Toulouse is working to strengthen the visibility of women in space public and promote substantive equality between women and men.
Gaëlle is one of the chosen women that has an inspiring life path and professional orientation that testify to great progress in terms of social roles traditionally attributed to women and men.
Loop extrusion story out in Nature!
Coline's paper is now out in Nature! It shows that TADs are needed for the establishment of yH2AX domains in a cohesin-mediated loop extrusion manner. A news and views by Leonid Minry nicely summarizes this article.
For more, also check on the CNRS website.
This review article in Nature Cell Biology discusses about the formation and function of R-loops that accumulate in cis to DSBs, especially those induced in transcriptionally active loci.
This paper shows that TADs are needed for the establishment of yH2AX domains in a cohesin-mediated loop extrusion manner. A news and views by Leonid Minry nicely summarizes this article.