In this Review article in Trends in Genetics,  we come back on recent mechanistic insights on the transcriptional repression that occur in cis to DSBs, and discuss how these mechanisms could drives the production of distinct RNA species at DSB sites

This article Nature shows that a novel chromatin compartment forms in response to DSB induction.

In this article posted on BioRxiv,  we report how chromatin accessibility is reshuffled at the damaged locus at high resolution. We show that resection-dependent chromatin remodeling events at individual damaged loci display significant heterogeneity in single cells, and can frequently be asymmetric and unidirectional. We also report that  coordinated chromatin accessibility patterns at multiple DSBs is ssociated with specific gene expression programs, including DNA damage checkpoint signaling, inflammation and apoptosis. 

This article in Mol Cell shows that, as persistent breaks in yeast, or heterochromatic breaks in drosophila, some DSBs (TC-DSBs, induced in active loci) can reloacte to the nuclear periphery in human cells.  At the nuclear enveloppe they are anchored via a protein of the LINC complex, Sun1 but not via Sun2. This process is under the control of PERIOD proteins, that are key factors ensuring circadian oscillations, and we report that consequently, TC-DSB repair is regulated by the cirdadian clock.