Research Interests

Our research aim is to understand the molecular mechanisms responsible for the maintenance of genome integrity. Our lab particularly focuses on DNA double strand break repair in the context of chromatin.

LATEST NEWS

BLM and BIR on bioRxiv

Here you'll find our new story on the Bloom helicase (BLM) and Break-induced replication (BIR) on bioRxiv

BLM BIR.JPG

May 2020

Quarantine

With the COVID19 pandemic, we're all at home, but still try to meet by video once a week. For full picture click here!

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March 2020

Loop extrusion in the formation of repair foci on bioRxiv

Here you'll find our new story about loop extrusion as a mechanism of DSB foci formation on  bioRxiv

loop extrusion DSB.JPG

May 2020

CNRS Silver Medal

Gaëlle was just announced to have obtained the Silver Medal of the CNRS!

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February 2020

RECENT ARTICLES

tools.JPG

February 2020

Studying DNA Double-Strand Break Repair: An Ever-Growing Toolbox 

This review in Frontiers in Molecular Biosciences discusses of the exisiting tools to study DNA double strand break repair

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m6A modififed R-loops.JPG

December, 2019

m6A RNA involvment in R-loop regulation  by Aline Marnef

This News and views  in Nature Genetics discusses the recent discovery that R-loops can be m6A modified and the impact on genome stability.

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secret life of chromosome.JPG

September, 2019

Chromosome loop upon DSB by Coline Arnould

This review in The Journal of Molecular Biology discusses the chromosome architecture, inter-chromosomal, and long-range contacts that take place following damage.

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