Research Interests
Our research aim is to understand the molecular mechanisms responsible for the maintenance of genome integrity. Our lab particularly focuses on DNA double strand break repair in the context of chromatin.
LATEST NEWS
Sarah, Aude and Ikrame's paper is out!
A POLD3/BLM dependent repair pathway handles DSBs upon the presence of excessive R-loops
April 2022
Emma Lesage PhD Defense
Congrats to Emma Lesage who succesfully obtained her PhD this 13th December!
December 2021
Unit retreat
We had a nice time at our unit (MCD) retreat!
March 2022
Welcome Laure and Emmanuelle
Welcome to Laure Guitton-Sert (post-doc) and Emmanuelle Maciel (PhD student) who recently joined the team!
December 2021
RECENT ARTICLES
June 2021
This review article in DNA repair discusses about the way DSBs occurring in actively transcribed loci are handled
April 2021
This review article in Nature Cell Biology discusses about the formation and function of R-loops that accumulate in cis to DSBs, especially those induced in transcriptionally active loci.
February 2021
This paper shows that TADs are needed for the establishment of yH2AX domains in a cohesin-mediated loop extrusion manner. A news and views by Leonid Minry nicely summarizes this article.